正高级职称人员

基本介绍

赵蔚 教授
干细胞
博士导师,硕士导师
干细胞 020-87334540
广州中山二路74号
zhaowei23@mail.sysu.edu.cn

个人简介:


 赵蔚,教授,国家青年千人。2004年和2009年于南京大学获生物学士和博士学位。2009年8月至2015年3月分别在美国Baylor College of Medicine从事博士后研究和康奈尔大学Weill医学院附属Methodist医院从事助理研究员工作。2015年通过中山大学“百人计划I类”和国家“千人计划青年项目”(第十一批)引进到中山大学中山医学院。赵蔚教授现在主要从事干细胞与癌症表观遗传学和表观遗传分子药理学的研究工作,在干细胞和肿瘤表观遗传调控与分子药理学等领域取得重要成果。迄今已在 Cell,LeukemiaNanoscale, Nature Communications 等国际权威学术期刊发表论文26篇。

近五年论文发表情况*

Chensong Huang (#); Junjun Chu(#) ; Xiaoxu Zhu; Jianhui Li; Xitai Huang; Jianpeng Cai; Wei Zhao(*) ; Xiaoyu Yin (*). The C/EBPβ-LINC01133 axis promotes cell proliferation in pancreatic ductal adenocarcinoma through upregulation of CCNG1, Cancer Lett., 2018.2.16, S0304-3835(18): 30153~30158

Wei Zhao(#) ; Peng Tan(#) ; Qingyuan Zhu(#) ; Adebusola Ajibade; Teng Long; Wenyong Long; Qingtian Li; Pinghua Liu; Bo Ning; Helen Y Wang; Rongfu Wang (*) Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer, J Mol Cell Biol., 2017.12.8, Epub ahead of print

Jingxin Mo(#) ; Li Wang(#) ; Xiaojia Huang; Bing Lu; Changye Zou; Lili Wei; Junjun Chu; Paul K. Eggers; Shen Chen; Colin L. Raston; Jun Wu(*) ; Lee Yong Lim(*); Wei Zhao (*). Multifunctional nanoparticles for co-delivery of paclitaxel and carboplatin against ovarian cancer by inactivating the JMJD3-HER2 axis, Nanoscale, 2017.9.14, 9(35): 13142~13152

Lili Wei(#) ; Yunfang Yang(#) ; Kun Shi; Jun Wu; ; Wei Zhao(*), Jingxin Mo(*). Preparation and Characterization of Loperamide-Loaded Dynasan 114 Solid Lipid Nanoparticles for Increased Oral Absorption In the Treatment of Diarrhea, Front Pharmacol, 2016.09.21, 7

Wei Zhao(#) ; Qingtian Li; Stephen Ayers; Yifeng Gu; Zhong Shi; Qingyuan Zhu; Yidong Chen; Helen Wang; Rongfu Wang(*) , Jmjd3 Inhibits Reprogramming by Upregulating Expression of INK4a/ Arf and Targeting PHF20 for Ubiquitination, Cell, 2013.2.28, 152(5): 1037~1050

Qingyuan Zhu(#) ; Peng Tan(#) ; Yinyin Li; Meng Lin; Chaoran Li; Jingrong Mao; Jun Cui; Wei Zhao; Helen Y Wang; Rongfu Wang(*). DHX29 functions as a RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity, PLoS Pathog, 2018.2.20, 14(2)

Wenyong Long(#); Wei Zhao (#); Bo Ning; Jing Huang; Junjun Chu; Linfeng Li; Qianquan Ma; Changsheng Xing; Helen Y Wang; Qing Liu; Rongfu Wang (*). PHF20 collaborates with PARP1 to promote stemness and aggressiveness of neuroblastoma cells through activation of SOX2 and OCT4., J Mol Cell Biol., 2018.2.14, Epub ahead of print

Chenglei Wu; Zexiong Su; Meng Lin; Jiayu Ou; Wei Zhao; Jun Cui(*) ; Rongfu Wang (*), NLRP11 attenuates Toll-like receptor signalling by targeting TRAF6 for degradation via the ubiquitin ligase RNF19A, Nat Commun., 2017.12.7, 8(1).

Chunliu Huang; Junjie Shi; Yibin Guo; Weijun Huang; Shanshan Huang; Siqi Ming; Xingui Wu; Rui Zhang; Junjun Ding; Wei Zhao; Jie Jia; Xi Huang; Andy Peng Xiang; Yongsheng Shi; Chengguo Yao (*), A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs., Nucleic Acids Res., 2017.9.6, 45(15): 8647~8660

Bo Ning; Wei Zhao; Chen Qian; Pinghua Liu; Qingtian Li; Wenyuan Li; Rongfu Wang (*), USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components, Nat Commun, 2017.8.24, 8 (1)

Wenyong Long(#) ; Yang Yi(#) ; Shen Chen; Qi Cao; Wei Zhao (*); Qing Liu (*). Potential New Therapies for Pediatric Diffuse Intrinsic Pontine Glioma, Front Pharmacol., 2017.7.25, 8(495) 

Fangkun Liu (#); Jing Huang(#); Bo Ning; Zhixiong Liu; Shen Chen(*) ; Wei Zhao(*). Drug Discovery via Human-Derived Stem Cell Organoids Front Pharmacol 2016.09.22, 7

Chenglei Wu; Yexin Yang; Jiayu Ou; Liang Zhu; Wei Zhao; Jun Cui(*). LRRC14 attenuates Toll-like receptor-mediated NF-kappaB signaling through disruption of IKK complex. , Exp Cell Res, 2016.9.10, 347(1): 65~73

Bing Lu; Xiaojia Huang; Jingxin Mo (*); Wei Zhao (*). Drug Delivery Using Nanoparticles for Cancer Stem-Like Cell Targeting, Frontiers in Pharmacology, 2016.04.12, 7.

Bo Ning; Wenyuan Li; Wei Zhao; Rongfu Wang (*). Targeting epigenetic regulations in cancer. , Acta Biochim Biophys Sin (Shanghai), 2016.1, 48(1): 97~109

Qingtian Li; Jia Zou; Mingjun Wang; Xilai Ding; Iouri Chepelev; Xikun Zhou; Wei Zhao; Gang Wei; Jun Cui; Keji Zhao; Helen Y Wang; Rong-Fu Wang (*). Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation. , Nat Commun, 2014.12.22, 5: 5780~5780

Mingjun Wang; Bingnan Yin; Satoko Matsueda; Lijuan Deng; Ying Li; Wei Zhao; Jia Zou; Qingtian Li; Christopher Loo; Rong-Fu Wang; Helen Y Wang (*). Identification of special AT-rich sequence binding protein 1 as a novel tumorantigen recognized by CD8+ T cells: implication for cancer immunotherapy. PLoS One, 2013, 8(2): e56730~e56730

主持或参加的在研科研项目:
1. 国家自然科学基金面上项目,2016-2019,项目负责人;
2. 国家自然科学基金面上项目,2018-2021,项目负责人;
3. 国家千人计划青年项目(第十一批)2016-2018,项目负责人;
4. 2017年国家重点研发计划干细胞及转化研究项目,子课题负责人
5. 2017年广东省“珠江人才计划”引进创新创业团队,第一核心成员;

 

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