Frontiers in Medical Sciences Lecture-320-Reserve Stem Cell and Drug-resistant Cancer Stem Cells

Author: ZSSOM    UpdateTime: 2018/03/02    Hits: 9

Chairs: Speaker1:Linheng Li, Investigator Stowers Institute for Medical Research,Speaker2:Xi (CiCi) He, Research Specialist Stowers Institute for Medical Research

Time: March6th, 2018 , At 15:30-17:00

Venue: Boai Meeting Room, 15th Floor, Science Building, Zhongshan School of Medicine, Sun Yat-sen University North Campus

About the speaker

Dr. Li obtained his Ph. D. degree in University of New York Medical Center(1995) and postdoctoral fellowship in University of Washington Medical Center (2000). From 2000 to present, Dr. Li is an Investigator inStowers Institute for Medical Research and a Co-Leader for University of Kansas Cancer Center. Dr. Li is a Fellow of the American Gastroenterological Association (AGA), a Fellow of the American Association for the Advancement of Science (AAAS), and an Editorial Board member for Cell Stem Cell journal. He recently serves as President for SCBA Hematology Division (2018). His laboratory studies the mechanisms that regulate stem cell function in hematopoietic and intestinal tissues and the ways in which those mechanisms get hijacked by cancer cells to enable tumor formation. Dr. Li has published more than 70 peer reviewed articles in high profile journals such as Nature, Sicence, Cell, Nature Medicine and Cell Stem Cell.


Dr. Heis a Research Specialist inStowers Institute for Medical Research.She actively contributed to study the HSC and Identification of HSC niche published as key co-author Blood 2003 and Nature 2003. Dr. He established the system for studying intestinal stem cells and continues leads the group to focus on intestinal stem cells and niches. She first reported to the intestinal field that loss of either Bmpr1a or PTEN resulted in a conversion from normal ISCs into tumor initiating cancer stem cells. These two works (He et al., Nature Genet, 2004; He et al., Nature Genet, 2007) has a significant impact to the field as indicated by very high citation (adding together >1000).

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