性      别: 女    

导    师: 硕士导师

学科专业: 生理学     

 


个人简介:

        辽宁抚顺人,医学博士,副教授,硕士导师,八年制医学生全程导师。2007年毕业于中山大学,获医学博士学位(生理学专业),2010年晋升为副教授。自2002年以来一直在中山大学疼痛研究中心从事病理性疼痛的中枢和外周机制研究。迄今已在国内外期刊发表论文20篇,其中SCI论文12篇(通讯作者、第一作者5篇)。主持国家自然科学基金(2项)、省级基金2项,获资助科研经费百万元。曾参与七项省部级以上科研基金(其中三项为主要参与者)、参与一项广州市科技计划项目。指导学生获大学生创新实验项目省级、国家级各一项,校级业余科研项目共3项。指导学生获2013年学生科研比赛校级挑战杯特等奖。获2012年中华医学科技奖三等奖(第四完成人)。参编教材1部。

 

 

重要学术研究成果与贡献:

1) Wei XH, Na XD, Liao GJ, Chen QY, Cui Y, Chen FY, Li YY, Zang Y(corresponding author), Liu XG. The up-regulation of IL-6 in DRG and spinal dorsal horn contributes to neuropathic pain following L5 ventral root transection. Exp Neurol. 2013 Mar; 241:159-68. ( SCI 2011=4.699)

2) Wei XH, Wei X, Chen FY, Zang Y, Xin WJ, Pang RP, Chen Y, Wang J, Li YY, Shen KF, Zhou LJ, Liu XG. The Upregulation of Translocator Protein (18 kDa) Promotes Recovery from Neuropathic Pain in Rats. J Neurosci. 2013 Jan 23;33(4):1540-51. ( SCI 2011=7.115)

3) Wei XH, Yang T, Wu Q, Xin WJ, Wu JL, Wang YQ, Zang Y, Wang J, Li YY, Liu XG. Peri-sciatic administration of recombinant rat IL-1β induces mechanical allodynia by activation of src-family kinases in spinal microglia in rats. Exp Neurol., 2012 Apr;234(2):389-97. (SCI 2011=4.699)

4) Zang Y(corresponding author), Xin WJ, Pang RP, Li YY, Liu XG. Upregulation of Nav1.3 channel induced by rrTNF in cultured adult rat DRG neurons via p38 MAPK and JNK pathways. Chin J Physiol., 2011;54(4):241-246(SCI 2011= 0.558)

5) Zhou LJ, Yang T, Wei X, Liu Y, Xin WJ, Chen Y, Pang RP, Zang Y, Li YY, Liu XG. Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat. Brain Behav Immun., 2011; 25(2):322-34.(SCI 2011= 4.72)

6)Zang Y, He XH, Xin WJ, Pang RP, Wei XH, Zhou LJ, Li YY, Liu XG. Inhibition of NF-kappaB prevents mechanical allodynia induced by spinal ventral root transection and suppresses the re-expression of Nav1.3 in DRG neurons in vivo and in vitro. Brain Res. 2010 Dec 2;1363:151-8. (SCI 2011= 2.728)

7) He XH, Zang Y(co-author), Chen X, Pang RP, Xu JT, Zhou X, Wei XH, Li YY, Xin WJ, Qin ZH, Liu XG. TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury. Pain, 2010 Nov;151(2):266-79. Comment in: Pain 2010 Nov;151(2):237-8.(SCI 2011= 5.777)

8) Gong QJ, Li YY, Xin WJ, Zang Y, Ren WJ, Wei XH, Li YY, Zhang T, Liu XG. ATP induces long-term potentiation of C-fiber-evoked field potentials in spinal dorsal horn: The roles of P2X(4) receptors and p38 MAPK in microglia. Glia. 2009; 57(6):583-91(SCI 2011=4.82)

9)Wei XH, Zang Y(co-author), Wu CY, Xu JT, Wu CY, Xin WJ, Liu XG. Peri-sciatic administration of recombinant rat TNF-α induces mechanical allodynia via upregulation of TNF-α in dorsal root ganglia and in spinal dorsal horn: The role of NF-kappa B pathway. Exp. Neurol. , 2007 Jun;205(2):471-84. (SCI 2011=4.699)

10) Xu JT, Xin WJ, Wei XH, Wu CY, Ge YX, Liu YL, Zang Y, Zhang T, Li YY, Liu XG. P38 Activation in Uninjured Primary Afferent Neurons and in Spinal Microglia Contributes to the Development of Neuropathic Pain Induced by Selective Motor Fiber Injury. Exp Neurol., 2007; 204(1): 355-65. (SCI 2011=4.699)

11) Xin WJ, Gong QJ, Xu JT, Yang HW, Zang Y, Zhang T, Li YY, Liu XG. Role of phosphorylation of ERK in induction and maintenance of LTP of the C-fiber evoked field potentials in spinal dorsal horn. J Neurosci. Res., 2006 Oct;84(5):934-43. (SCI 2011= 2.738)

12) Xu JT, Xin WJ, Zang Y, Wu CY, Liu XG. The Role of Tumor Necrosis Factor-Alpha in the Neuropathic Pain Induced by Lumbar 5 Ventral Root Transection in Rat. Pain, 2006; 123(3): 306-21. (SCI 2011= 5.777)

 

学术论著与教材:

参编全国普通高等教育医学类系列教材《生理学》(第二版) 刘先国主编 科学出版社(ISBN 978-7-03-029324-4)

 

学术兼职:

广东省神经科学学会会员,广东省医学会疼痛分会会员,中国神经科学学会会员,中国生理学会会员,广东省生理学会会员