个人简介:

    医学博士,教授,博士导师,八年制医学生全程导师,广东省博士后理事会副理事长,广东省寄生虫学会秘书长,玛希隆大学(Mahidol University)客座教授。2005年于中南大学湘雅医学院获医学博士学位,2007年于中山大学中山医学院博士后出站并留校。近年来一直从事分子病原生物学、病原疫苗开发与药物研制、重要入侵病原快速溯源等领域的研究工作。主持国家重点研发项目课题、国家自然科学基金(3项)、广东省国际科技合作重点项目等15项课题,经费总额超过600万。在国内外专业学术期刊发表论文50余篇,其中SCI论文30余篇(通讯作者、第一作者20篇)。2010年赴德国马普分子遗传学研究所进行科研交流与合作。2012年被选拔为国家留学基金“青年骨干教师”赴美国韦恩州立大学医学院公派留学一年。主编、参编教材8部,主持3项教学改革项目(含1项重点项目)。指导学生3次获得“全国大学生基础医学创新论坛暨实验设计大赛”一等奖,并获国家大学生创新训练项目(2项)、广东省大学生创新训练项目及中山大学医科学生业余科研暨科研助理计划等项目资助。

导    师:博士导师,硕士导师

学科专业:病原生物学

重要学术研究成果与贡献:

 

学术论著与教材:

1. Wu Y, Liu J, Lin Y, Weng R, Chen R, Li J, Lv Z. Diagnosis, Monitoring, and Control of Schistosomiasis-An Update. J Biomed Nanotechnol. 2018,14(3):430-455.

 

2. Mengying Z, Yiyue X, Tong P, Yue H, Limpanont Y, Ping H, Okanurak K, Yanqi W, Dekumyoy P, Hongli Z, Watthanakulpanich D, Zhongdao W, Zhi W, Zhiyue L. Apoptosis and necroptosis of mouse hippocampal and parenchymal astrocytes, microglia and neurons caused by Angiostrongylus cantonensis infection. Parasit Vectors. 2017,10(1):611

 

3. Wang M, Wu L, Weng R, Zheng W, Wu Z, Lv Z. Therapeutic potential of helminths in autoimmune diseases: helminth-derived immune-regulators and immune balance. Parasitol Res. 2017,116(8):2065-2074.

 

4. Lu XT, Gu QY, Limpanont Y, Song LG, Wu ZD, Okanurak K, Lv ZY. Snail-borne parasitic diseases: an update on global epidemiological distribution, transmission interruption and control methods. Infect Dis Poverty. 2018,7(1):28.

 

5. Wang L, Xie H, Xu L, Liao Q, Wan S, Yu Z, Lin D, Zhang B, Lv Z, Wu Z, Sun X. rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-α Signaling Pathway. Theranostics. 2017,7(14):3446-3460.

 

6. Zheng S, Zhu Y, Zhao Z, Wu Z, Okanurak K, Lv Z. Liver fluke infection and cholangiocarcinoma: a review. Parasitol Res. 2017,116(1):11-19.

 

7. Ji L, Yiyue X, Xujin H, Minghui Z, Mengying Z, Yue H, Yanqi W, Langui S, Xin Z, Datao L, Shuo W, Huanqin Z, Zhongdao W, Zhiyue L. Study on the tolerance and adaptation of rats to Angiostrongylus cantonensis infection. Parasitol Res. 2017,116(7):1937-1945.

 

8. Wuhao L, Ran C, Xujin H, Zhongdao W, Dekumyoy P, Zhiyue L. Parasites and asthma. Parasitol Res. 2017,116(9):2373-2383.

 

9. He P, Song LG, Xie H, Liang JY, Yuan DY, Wu ZD, Lv ZY. Nucleic acid detection in the diagnosis and prevention of schistosomiasis. Infectious Diseases of Poverty. 2016,5:25.

 

10. Song LG, Wang XW, Yang Z, Lv ZY, Wu ZD. Angiostrongylus cantonensis in the vector snails Pomacea canaliculata and Achatina fulica in China: A meta-analysis. Parasitol Res. 2016, 115(3):913-923.

 

11. Liu J, Pan T, You X, Xu Y, Liang J, Limpanont Y, Sun X, Okanurak K, Zheng H, Wu Z, Lv Z. SjCa8, a calcium-binding protein from Schistosoma japonicum, inhibits cell migration and suppresses nitric oxide release of RAW264.7 macrophages. Parasit Vectors. 2015,8:513.

 

12. Feng F, Feng Y, Liu Z, Li WH, Wang WC, Wu ZD, Lv ZY. Effects of albendazole combined with TSII-A (a Chinese herb compound) on optic neuritis caused by Angiostrongylus cantonensis in BALB/c mice. Parasit Vectors. 2015,8:606.

 

13. Lv Z, Wu Z, Zhang L, Ji P, Cai Y, Luo S, Wang H, Li H. Genome mining offers a new starting point for parasitology research. Parasitol Res. 2015,114(2):399-409.

 

14. Wei J, Wu F, He A, Zeng X, Ouyang LS, Liu MS, Zheng HQ, Lei WL, Wu ZD,Lv ZY . Microglia activation: one of the checkpoints in the CNS inflammation caused by Angiostrongylus cantonensis infection in rodent model. Parasitol Res. 2015,114(9):3247-3254.

 

15. Ji PY, Hu HL, Yang XY, Wei XX, Zhu CC, Liu JC, Feng Y, Yang F, Okanurak K, Li N, Zeng X, Zheng HQ, Wu ZD, Lv ZY. AcCystatin, an immunoregulatory molecule from Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat model of asthma. Parasitol Res. 2015,114(2):613-624.

 

16.Yang F, Long E, Wen J, Cao L, Zhu C, Hu H, Ruan Y, Okanurak K, Hu H, Wei X, Yang X, Wang C, Zhang L, Wang X, Ji P, Zheng H, Wu Z ,Lv Z. Linalool, derived from Cinnamomum camphora (L.) Presl leaf extracts, possesses molluscicidal activity against Oncomelania hupensis and inhibits infection of Schistosoma japonicum. Parasit Vectors. 2014, 7:407.

 

17.Li S, Yang F, Ji P, Zeng X, Wu X, Wei J, Ouyang L, Liang J, Zheng H, Wu Z, Lv Z. Eosinophil chemotactic chemokine profilings of the brain from permissive and non-permissive hosts infected with Angiostrongylus cantonensis. Parasitol Res. 2014, 113(2):517-525.

 

18.Zeng X, Wang J, Wei J, Wu F, Fung F, Wu X, Sun X, Zheng H, Lv Z, Wu Z. Angiostrongylus cantonensis: tegumental and hypodermic alterations of the fourth-stage larvae following administration of tribendimidine in vivo and in vitro. Parasitol Res. 2013,112(8):3035-3040.

 

19.Han YP, Li ZY, Li BC, Sun X, Zhu CC, Ling XT, Zheng HQ, Wu ZD, Lv ZY. Molecular cloning and characterization of a cathepsin B fromAngiostrongylus cantonensis. Parasitol Res. 2011, 109(2):369-378.

 

20.Liu YH, Han YP, Li ZY, Wei J, He HJ, Xu CZ, Zheng HQ, Zhan XM, Wu ZD, Lv ZY. Molecular cloning and characterization of cystatin, a cysteine protease inhibitor, from Angiostrongylus cantonensis. Parasitol Res. 2010,107(4):915-922.

 

21.Lv ZY, Yang LL, Hu SM, Sun X, He HJ, He SJ, Li ZY, Zhou YP, Fung MC, Yu XB, Zheng HQ, Cao AL, Wu ZD. Expression profile, localization of an 8-kDa calcium-binding protein from Schistosoma japonicum (SjCa8), and vaccine potential of recombinant SjCa8 (rSjCa8) against infections in mice. Parasitol Res. 2009,104(4):733-743.

 

获奖及荣誉:

     2010年入选为广东省高等学校“千百十”工程培养对象。2012年至今3次评为中山大学“优秀学生导师”。2014年、2016年评为中山大学“优秀党员”。2018年被评为中山大学“优秀党务工作者”、中山医学院“优秀教师”。

学术兼职:

《Infectious Diseases of Poverty》、《Parasites & Vectors》、《Acta Tropica》、《Parasitology Research》、《Cytotechnology》《中国血吸虫病防治》、《热带医学杂志》审稿人

其 他:

     常年招收医学、药学和生物学专业的博士后及专职科研人员,诚挚欢迎加入团队!