学 术 报 告:Bioinformatics and Biocomputing
题 目:Bioinformatics and Biocomputing
主讲人:吴智君教授
Department of Mathematics,Program on Bioinformatics and Computational Biology,Iowa State University
主持人:刘燕副教授
中山医学院生物医学工程系副主任
时 间:2008年05月29日(星期四) 下午15:00时
地 点:中山大学北校区永生楼第七课室
吴智君(Zhijun Wu)教授简介:
Professional Experience
1. Professor, Department of Mathematics, Program on Bioinformatics and Computational Biology, Iowa State University, 2008 --
2. Associate Professor, Department of Mathematics, Program on Bioinformatics and Computational Biology, Iowa State University, 2000 -- 2008
3. New Direction Research Professor, Institute for Mathematics and Its Applications, University of Minnesota, Minneapolis, Minnesota, September 2007 – June 2008
Research Interests
1. Computational Biology: Molecular distance geometry, protein structure refinement, simulation of transition of protein conformation, constrained molecular dynamics, potential energy minimization, protein geometry databases, multiscale protein modeling, metabolic network simulation and optimization
2. Computational Mathematics: Numerical linear algebra, nonlinear optimization, linear programming, integer and combinatorial optimization, numerical solution of ordinary and partial differential equations, parallel high-performance computing
Refereed Publications:(2005-)
1. Refinement of NMR-Determined Protein Structures with Database Derived Mean Force Potentials, Proteins: Structure, Function, Bioinformatics (published online in 2007: DOI: 10.1002/prot.21358), Vol. 68, 2007, pp. 232-242 (with Di Wu and Robert Jernigan)
2. PIDD: A Protein Inter-atomic Distance Distribution Database, Journal of Nucleic Acid Research (published online in 2006: DOI: 10.1093/nar/gkl802), Vol. 35, 2007, pp. D202-D207 (with Di Wu, Feng Cui, and Robert Jernigan)
3. An Updated Geometric Buildup Algorithm for Solving the Molecular Distance Geometry Problem with Sparse Distance Data, Journal of Global Optimization (published online in 2006: DOI 10.1007/s10898-006-9080-6), Vol. 37, No. 4, 2007, pp. 661-673 (with Di Wu)
4. Refinement of NMR-Determined Protein Structures with Database Derived Distance Constraints, Journal of Bioinformatics and Computational Biology, Vol. 3, 2005, pp. 1315-1330 (with Feng Cui and Robert Jernigan)
欢迎各位师生踊跃参加!
中山大学中山医学院
中山大学医学科学处
2008年05月26日