医学前沿学术报告第188期—Modular membrane fusion machines: the reovirus FAST proteins

题 目：Modular membrane fusion machines: the reovirus FAST proteins

主讲人：Roy Duncan, PhD

            Professor, Department of Microbiology and

            Immunology, Dalhousie University, Canada

主持人：潘春根 副教授

           中山医学院人类病毒学研究所

时   间：2014 9月4日（星期四）下午16:00时

地   点：中山大学北校区科技综合楼15楼博学厅

主讲人简介：

Dr. Duncan’s research group discovered the only known examples of membrane fusion proteins encoded by non-enveloped viruses. These reovirus Fusion-Associated Small Transmembrane (FAST) proteins define a new family of viral fusogens, the smallest known membrane fusion proteins and the only example of viral fusogens specifically adapted to mediate cell-cell membrane fusion and syncytium formation. These nonstructural viral proteins are virulence determinants of the fusogenic reoviruses, and they employ a novel combination of structural motifs to mediate membrane fusion. This presentation will focus on recent structural and functional investigations into the mechanism of action of the FAST proteins, and the involvement of cellular proteins and pathways in cell-cell fusion events. 

欢迎各位师生踊跃参加！

                                                                           中山大学中山医学院

                      中山大学医学科学处

                                                                             2014年8月19日